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The combined environment of low energy availability, reduced mechanical loading (if activity decreases), and hormonal shifts creates a "perfect storm" for sarcopenia

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Baseline WOMAC pain score: 6.0 Reduction at 80 weeks: 4.3 points Percent reduction: 73.1% A 73% drop in joint-pain scores is the kind of effect usually associated with a dedicated analgesic or joint intervention, not a metabolic drug

When I see the GLP-1 craze, I think about how peoples lives have been ruined by opioids like Oxycontin